lunes, 10 de enero de 2011

TB and HIV in children - advances in prevention and management.

Interesante artículo, debemos pensar un poco más en la Co- infección. Aqui les mando el abstract y el link, este no esta disponible sin subscripción. Pero pueden pedirlo y comprarlo a quien esté interesado.

Paediatr Respir Rev. 2011 Mar;12(1):39-45. Epub 2010 Oct 18.

Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, South Africa. bjmarais@sun.ac.za

Abstract

The human immunodeficiency virus (HIV) epidemic has had a major impact on the age and gender profile of adult tuberculosis (TB) patients, resulting in increased exposure of HIV-infected and uninfected children at a very young age. Young and/or HIV-infected children are extremely vulnerable to develop severe forms of TB following recent exposure and infection. There is an urgent need to implement safe and pragmatic strategies to prevent TB in children, especially in TB endemic areas where they suffer the greatest burden of disease. The management of TB in HIV-infected children poses multiple challenges, but recent advances in the implementation of prevention of mother to child transmission (PMTCT) strategies and HIV care of infants offer hope. These include HIV testing and access to PMTCT for all pregnant women, routine testing of all HIV exposed infants and rapid initiation of antiretroviral treatment irrespective of clinical or immunological disease staging. In addition, careful scrutiny for TB exposure should occur at every health care visit, with provision of isoniazid preventive therapy (IPT) following each documented exposure event. Knowing the HIV infection status of child TB suspects is essential to optimize case management. Although multiple difficulties remain, recent advances demonstrate that the management of children with TB and/or HIV can be vastly improved by well focused interventions using readily available resources.
2010 Elsevier Ltd. All rights reserved.
 
Link: http://www.ncbi.nlm.nih.gov/pubmed/21172674

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