"Mild neurological impairment remains common in HIV-infected patients.
Before the advent of potent combination antiretroviral therapy (ART), neurological disease, including HIV-associated dementia (HAD), was common in HIV-infected individuals. How prevalent is such disease in the current HIV treatment era? Baseline data from the NIH-supported CHARTER study provide some insight.
A total of 1555 HIV-infected patients at six U.S. academic centers underwent extensive neurocognitive testing and psychiatric evaluation; 71% were receiving combination ART. Patients were categorized according to whether they had comorbidities that could cause neurocognitive impairment: 15% had confounding comorbidities severe enough to preclude diagnosing HIV-associated neurological disease, 30% had potentially contributing comorbidities, and 54% had other or no comorbidities.
Overall, 814 patients (52%) had neurocognitive impairment — 83% of those with confounding comorbidities, 59% of those with contributing comorbidities, and 40% of those with other or no comorbidities. In the latter two groups, 33% of patients had neurocognitive impairment that did not influence their everyday functioning, 12% had mild neurocognitive impairment, and 2% had HAD.
HIV-associated factors were associated with neurocognitive impairment only in the group with the least comorbidity. In that group, neurocognitive impairment was associated with both an AIDS diagnosis and a lower nadir CD4-cell count. Patients on ART had a higher prevalence of neurocognitive disease than those not on ART. However, the lowest rate among patients on ART was in those with both a nadir CD4 count
200 cells/mm3 and an undetectable viral load.Comment: This study documents a continued high prevalence of neurocognitive impairment in the HIV-infected population. Some of the impairment is likely attributable to the infection itself and some to common comorbidities. Longitudinal data from this study should help to define the effect of ART on neurological conditions."
Link para mayor informafción para el tema: http://infectious-diseases.jwatch.org/cgi/content/full/2010/1215/2?q=etoc_jwneuro
Dr. Carlos Erazo
Great Dr. imoloa herbal medicine is the perfect cure for the HIV virus, I was diagnosed of HIV for 8 years, and every day I always looking for research to find the perfect way to get rid of this terrible disease because I always know that what we need because our health is on earth . So, on my internet search I saw several testimonies about how Dr. imoloa can cure HIV with powerful herbal medicines. I decided to contact this man, I contacted him for herbal medicines that I received via DHL courier service. And he guided me how. I asked him for a solution to take herbal medicine for two weeks. And then he instructed me to go check what I was doing. Look at me (HIV NEGATIVE). Thank God for Dr. Imoloa for using a powerful herbal remedy to cure me. he also has a cure for diseases such as Parkison's disease, vaginal cancer, epilepsy, anxiety disorders, autoimmune diseases, back pain, sprains, bipolar disorder, brain tumors, malignant, bruxism, bulimia, cervical disc disease, cardiovascular disease, cardiovascular disease, sprains, bipolar disorder, brain tumors, malignant, bruxism, bulimia, cervical disc disease, cardiovascular disease, cardiovascular disease, sprains, bipolar disorder, brain tumors, malignant, bruxism, bulimia, cervical disc disease, cardiovascular disease , chronic respiratory diseases, mental and behavioral disorders, Cystic Fibrosis, Hypertension, Diabetes, asthma, autoimmune mediated arthritis. Chronic kidney disease, arthritis, back pain, impotence, feta alcohol spectrum, Dysthymic Disorders, Eczema, skin cancer, tuberculosis, Chronic Fatigue Syndrome, constipation, inflammatory bowel disease, bone cancer, lung cancer, mouth sores, oral cancer, body pain, fever, hepatitis ABC, syphilis, diarrhea, Huntington's disease, back acne, chronic kidney failure, Addison's disease, Chronic Disease, Crohn's Disease, Cystic Fibrosis, Fibromyalgia, Inflammatory Bowel Disease, Fungal Nail Disease, Paralysis, Celia Disease , Lymphoma, Major Depression, Malignant Melanoma, Mania, Melorheostosis, Meniere's Disease, Mucopolysaccharidosis, Multiple Sclerosis, Muscle Dystrophy, Rheumatoid Arthritis, Alzheimer's Disease email- drimolaherbalmademedicine@gmail.com / or {whatssapp .....+2347081986098}
ResponderEliminar