lunes, 5 de diciembre de 2011

La epidemiologia de HPV en mujeres VIH positivas y VIH negativas .

Estimados colegas les dejo aquí este artículo y el link donde pueden bajarse el pdf.

http://www.biomedcentral.com/1471-2334/11/333/abstract

Saludos 


Dr. Carlos Erazo

Research article

The epidemiology of human papillomavirus infection in HIV-positive and HIV-negative high-risk women in Kigali, Rwanda

Nienke J Veldhuijzen, Sarah L Braunstein, Joseph Vyankandondera, Chantal Ingabire, Justin Ntirushwa, Evelyne Kestelyn, Coosje Tuijn, Ferdinand W. Wit, Aline Umutoni, Mireille Uwineza, Tania Crucitti and Janneke HHM van de Wijgert

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BMC Infectious Diseases 2011, 11:333 doi:10.1186/1471-2334-11-333
Published: 2 December 2011

Abstract (provisional)

Background

The prevalence, incidence and persistence of human papillomavirus (HPV) types in sub-Saharan Africa are not well established. The objectives of the current study are to describe (predictors of) the epidemiology of HPV among high-risk women in Kigali, Rwanda.

Methods

HIV-negative, high-risk women were seen quarterly for one year, and once in Year 2. HIV serostatus, clinical, and behavioral information were assessed at each visit, HPV types at Month 6 and Year 2, and other sexually transmitted infections (STI) at selected visits. HPV prevalence was also assessed in HIV-positive, high-risk women.

Results

Prevalence of any HPV was 47.0% in HIV-negative women (median age 25 years) compared to 72.2% in HIV-positive women (median age 27 years; OR 2.9, 95% CI 1.9-4.6). Among HIV-negative women, cumulative incidence of high-risk (HR)-HPV was 28.0% and persistence 32.0% after a mean period of 16.6 and 16.9 months, respectively. Prior Chlamydia trachomatis and Neisseria gonorrhoeae infection, concurrent low-risk (LR)-HPV infection and incident HSV-2 were associated with HR-HPV prevalence among HIV-negative women; prior C. trachomatis infection and co-infection with LR-HPV and HPV16-related HPV types with HR-HPV acquisition. HPV16-related types were the most prevalent and persistent.

Conclusions

High HPV prevalence, incidence and persistence were found among high-risk women in Kigali. HPV52 had the highest incidence; and, together with HPV33 and HPV58, were strongly associated with acquisition of other HR-HPV types in HIV-negative women.

1 comentario:

  1. Hola un favor talvez me puedes ayudar con algun dato de prevalencia de hpv en mujeres vih positivo en ecuador, gracias

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